후부다형각막이상증의 공초점주사현미경소견

Confocal Microscopic Findings in Posterior Polymorphous Corneal Dystrophy

Purpose: To analyze the features of corneal tissue in patients with posterior polymorphous corneal dystrophy (PPMD) using in vivo confocal microscopy (IVCM). Case summary: Three patients with clinically diagnosed PPMD were examined using IVCM. Cross-sectioned corneal images of the corneal epithelium, Bowman’s layer, stromal layer, Descemet’s membrane, and endothelium were evaluated. IVCM demonstrated a depressed crater-like lesion, hyper-dense streak-like lesion, and surface irregularity of the corneal endothelium. Endothelial hypo-reflective vesicular and band-like lesions were also found. Pleomorphism and polymegathism were present with guttae and hyper-reflective endothelial nuclei. Conclusions: IVCM is a non-invasive and effective tool to diagnose PPMD. J Korean Ophthalmol Soc 2013;54(11):1783-1787