정상 한국인에서 연령에 따른 망막 혈관 직경과 관련 인자에 대한 분석

Analysis of Factors Associated with Retinal Vascular Caliber in Normal Korean Subjects

Purpose: To measure the diameter of the retinal arterial and venous caliber of normal Korean subjects and evaluate the factors affecting these diameters. Methods: Fundus photography was performed on 152 normal Korean subjects. Central retinal artery equivalent (CRAE) and central retinal vein equivalent (CRVE) were measured with a computer-based program (IVAN), and were used to investigate the relationship between the diameter and factors including age, gender, hypertension, diabetes, and smoking. Results: Among the study subjects, the CRVE was 209.33 ± 12.40 μm and the CRAE was 149.70 ± 9.01 μm. The CRVE and CRAE decreased with increasing age in all study subjects (both <em>p</em> < 0.001). There were significant gender differences in the CRVE and CRAE (p = 0.002, <em>p</em> = 0.042, respectively). After adjusting for age and gender, the hypertension group showed smaller CRVE and CRAE than the non-hypertension group (<em>p</em> = 0.038, <em>p</em> = 0.032, respectively). Smoking and diabetes were not significant factors affecting the CRAE and CRVE (both <em>p</em> > 0.05). Conclusions: In our study group, retinal vascular caliber of normal Korean subjects decreased with aging. Retinal vascular caliber was affected by gender and hypertension, but not by smoking and diabetes. J Korean Ophthalmol Soc 2014;55(4):548-554