건성안 지표와 서로 다른 두 기기로 측정된 전면 각막 고위수차의 관계 분석

Relationship between Dry Eye Parameters and Anterior Corneal Higher‐Order Aberrations Measured by Two Different Instruments

Purpose: To compare the corneal first surface higher-order aberrations (HOAs) of normal subjects and patients with dry eye using KR-1W<SUP>&#9415; (Topcon Corp., Tokyo, Japan) and Pentacam<SUP>&#9415; HR (Oculus Inc., Dutenhofen, Germany). We analyzed the relationship between the aberrations and the diagnostic parameters of dry eye. Methods: We evaluated anterior corneal HOAs in 71 normal eyes and 71 dry eyes using KR-1W<SUP>&#9415; and Pentacam<SUP>&#9415;. Dry eye patients were examined for fluorescein staining, tear break-up time (TBUT), and Schirmer I test. Ocular Surface Disease Index (OSDI) was used for assessment of subjective symptoms in dry eye patients. Results: HOAs measured by both instruments were greater in the dry eye group than in the control group, although HOAs using KR-1W<SUP>&#9415; only achieved statistical significance. The anterior corneal HOAs measured by the 2 instruments were significantly correlated with superficial punctate keratitis. Moreover, TBUT and the Shirmer I test negatively correlated, and OSDI positively correlated, with anterior corneal HOAs. Conclusions: The HOAs in patients with dry eye were significantly different from controls and tended to increase with disease severity. KR-1W<SUP>&#9415; might be more useful than Pentacam<SUP>&#9415; to detect tear film instabilities. J Korean Ophthalmol Soc 2015;56(1):6-12