학술저널
염산부플로메딜 정과 염산티클로피딘 정의 용출시험법 개발
Development of Dissolution Test Method for Buflomedil Hydrochloride Tablets and Ticlopidine Hydrochloride Tablets
- 대한약학회
- 약학회지
- 제56권 제4호 (2012년)
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2012.08211 - 216 (6 pages)
- 4
Drug dissolution test has been used for the purpose of both quality control of solid oral dosage forms and predicting in vivo drug release profiles. In this study, the dissolution profiles of buflomedil hydrochloride tablets and ticlopidine hydrochloride tablets were investigated according to the “Guidelines on Specifications of Dissolution tests for Oral dosage forms” of Korean Pharmacopoeia (KP). The analytical method using HPLC was validated. The validation was performed in terms of specificity, linearity, accuracy, precision and limit of quantitation.
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