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Synthesis of 8-Cycloalkoxychrysin Analogs and their Inhibitory Activity Against NO Production
- 대한약학회
- 약학회지
- 제59권 제1호 (2015년)
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2015.0212 - 16 (5 pages)
- 16
Several 8-cycloalkoxychrysin analogs were synthesized from 6-benzyloxy-5,8-dihydroxyflavone and cycloalkanols in 2 steps and we evaluated their inhibitory activities against NO production from LPS-induced RAW 264.7 cells. Among tested analogs, two analogs with cyclopentyl substructure (796 and 798) showed strong inhibitory activity against NO production.
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