하구순의 과립세포종 증례보고

Granular Cell Tumor in the Lower Lip：A Case Report

Purpose ：Granular cell tumour(GCT) is a rare benign tumour that can arise in anywhere throughout the body. Histopathological diagnosis of malignancy is difficult. We report a case of a granular cell tumor which developed on lower lip. Methods ：A 58-year-old male had a palpable mass and whitish plaque in the oral mucosa for three months. Results ：Under local anasthesia, the tumor was removed through wide excision including normal skin mar-gin. Immediate reconstruction using local flap was done. Pathologic observation showed nests of polygonal cells with abundant granular, eosinophilic cytoplasm and round nuclei. Immunohistopathologic staining showed posi-tive reaction on S-100 protein Conclusion ：The results support the hypothesis that granular cell tumor is derived from Schwann cells. We report here on a case of granular cell tumor of lower lip that was successfully treated with radical resection.