불발효차와 발효차의 간섬유화 억제 효능 비교

Preventative Effects of Green, Oolong and Black Teas on Hepatic fibroblast in LI90 Cell

Green tea and black tea are commonly drunk in the Asian and Western countries. It is known that the major tea catechins, (-)-epicatechin, (-)-epigallocatechin, (-)-epigallocatechin gallate, and (-)-epicatechin gallate are epimerized by fermentation processing. In this study, the effects of the extracts of the non-fermented and fermented teas on hepatic fibrosis were examined by means of the in vitro collagen secretion and collagen promoter assay. As a result, the treatment with green tea extract was found to reduce the secretion of collagen into the media, whereas black tea extract increased it, in the human hepatic stellate cell line.