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학술저널

댕댕이나무(Lonicera coerulea var. edulis) 열매의 항염증 효과 연구

Anti-inflammatory activity of the Fruits of Blue Honeysuckle

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In this study, we demonstrated the anti-inflammatory activities of two kinds of blue honeysuckle (Lonicera caerulea var. edulis Turcz, Lonicera caerulea var. longibracteata f. ovata Hara) extracts in the LPS-stimulated macrophages. These two extracts showed non-cytotoxic activity, even at the high concentration. These two extracts of honeysuckle reduced the production of nitric oxide, cyclooxigenase-2 and pro-inflammatory cytokines. The inhibitory activities of two extracts of honeysuckle were found to be caused by blockage of NF-κB activation.

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