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산자나무열매 유래 천연 히드록시신남아마이드의 실용적 합성

Practical Synthesis of a Natural Hydroxycinnamide Derived from Hippophae rhamnoides L.

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A practical synthesis of natural hydroxycinnamide derived from Hippophae rhamnoides L. has been accomplished. One-pot protection/deprotection and amidation of 4-hydroxycinnamic acid afforded the purposed cinnamide in good yield. The spectral data of synthesized cinnamide were in excellent agreement with the reported data. This synthetic procedure would facilitate synthesis of the natural hydroxycinnamides, and their biological studies.

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