경구 bisphosphonate를 복용하는 환자에서 발생한 bisphosphonate-related osteonecrosis of jaw에 대한 임상적 특징 및 처치:

Clinical feature and treatment of bisphosphonate-related osteonecrosis of jaw about oral bisphosphonate administrated patients: case reports

Bisphosphonates are used effectively for many medical conditions, such as multiple myeloma, Paget’s disease, osteoporosis, etc. However, recently, osteonecrosis of the jaw was observed in patients receiving long-term bisphosphonate therapy, including oral administration. This osteonecrosis is refractory, and complete recovery is not guaranteed despite a standard treatment protocol being established by many associations related to oral and maxillofacial surgery. The treatment outcome of oral bisphosphonate-related osteonecrosis of jaw (BRONJ) is reported with a review of the relevant literature.