Flavonoid의 흡수·대사

A Review of the Absorption and Metabolism of Flavonoids Focusing on Catechins

Catechins are one group of the most characteristic constituents containing in tea, fruits, and vegetables. A lot of studies have shown that catechin intake is associated with lower risk of various diseases such as cardiovascular, diabetes, and cancer. Recently, various researches on absorption and metabolism of flavonoids including catechins have been reported. Absorption and metabolic studies have shown that the in vivo circulating form of most flavonoids is conjugates such as sulfate and/or glucuronide with or without O-methylation, with a few notable exceptions. It is very important to know the absorption and metabolic conversion of flavonoids involving bioavailability, pharmacokinetics, and urinary excretion in order to evaluate their in vivo bioactivities after intake. This review provides details on the absorption and metabolism of catechins including several flavonoids.