염증성 호흡기 질환에서 기도점액 과다분비의 병태생리학적 의의 및 조절 방법 탐색
Pathophysiological Significance of Hypersecretion of airway Mucus in Inflammatory Pulmonary Disease and Investigation of Strategies of its Regulation
- 대한약학회
- 약학회지
- 제61권 제1호(2017년)
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2017.0230 - 40 (11 pages)
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DOI : 10.17480/psk.2017.61.1.30
- 144
Airway mucus is pivotal for physiological defense against invading particles, chemicals and pathogenic microbes. However, any abnormality of mucins can cause altered airway physiology and impair host defenses leading to severe diseases e.g. asthma and chronic obstructive pulmonary disease. Therefore, in this review, we discussed the recent progress in the field of research on the regulation of the gene expression, production and secretion of airway mucins, in order to make us try to develop the novel efficacious drug candidate for controlling the pathologic hypersecretion of airway mucins.
기도 점액 과다분비 질환의 병태생리
기도 점액 과다분비 질환의 조절 방법론
기도 점액 과다분비 질환의 치료제 개발 전략
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