가령에 따른 백서의 하악와 섬유층 세포내 Vimentin 면역양성 중간세사의 출현

PRESENCE OF VIMENTIN IMMUNOREACTIVE FILAMENTS IN THE CELLS OF MANDIBULAR FOSSA FIBROUS LAYER OF RAT WITH AGING

The purpose of this study was to investigate what the intermediate filaments in the cells of rat mandibular fossa fibrous fibrous layer are and any relationships between the presence of these filaments and aging. Mandibular fossae of 4 groups of rats(14-day, 28-day, 55-day and adult groups) were removed en bloc and processed for immunostaining and were subjected to light microscopic examination. The results were as follows: In 14-day group, there were no immunoreactive cells in fibrous layer of mandibular condyle articular surface. But in 28-day group, many immunoreactive cells were seen in fibrous layer, especially central portion of articular surface of mandibular fossa. These cells were fusiform shaped and immunoreactivities were seen in the cytoplasm around the nucleus. In 55-day group many immunoreactive cells were seen in fibrous layer of mandibular fossa. These cells were fusiform shaped and distributed evenly in central portion of this fibrous layer. Immunoreactivities were sseen in the cytoplasm around the nucleus. In adult group, the results were similar to 55-day group. Many immunoreactive cells were seen in fibrous layer of mandibular fossa especially central portion. According to these results, vimentin immunoreactive filaments appear with aging and increment of mechanical load associated with incision or mastication.