악하선 타석증에 관한 임상 및 병리조직학적 연구

A clinical and histopathologic study on the sialolithiasis of the submandibular gland

The authors have reviewed 12 cases of salivary stones in the submandibular glands. And the salivary stones were examined by scanning electron microscopy-energy dispersive spectroscopy(SEM-EDS) and X-ray diffraction analysis. The results were as follows ; 1. The incidence is higher in the 2nd and 3rd decades and prevalent in male. 2. The salivary stones mostly were found as a solid bloc(in 9 cases of 12 cases). 3. 8 cases of sialoliths could be surgically removed by an intraoral approach (sialolithotomy) and 4 cases required sialadenectomy. 4. The scanning electron microscopy disclosed a lamellar structure of a sialolith in low magnification, and a few dense cores were seen in the central area of the cracked surface. The perilamellar portions revealed colonized bacilli or cocci and some fungal hyhae and the middle layer consisted of fossilized bacterial and various mineral crystals. 5. SEM-EDS analysis showed that Ca and P were the major elements of the stones, frequently accompanied by Mg, Cl, and Fe. 6. By X-ray diffraction analysis, the main constituents of salivary stones were found to be apatite and whitlockite.