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학술저널

악골에 이환된 Histiocytosis X의 치험례

Histiocytosis X of the Maxilla

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Since the nonlipid reticuloendotheliosis which include eosinophilic granuloma. Hand-Schuller-Christian disease, Letterer-Siwe disease were first described by Hand in 1983, many clinicians reported various diseases similar to the above. Because the cause and the clinical and microscopic features of these various disease were not known, this disorder is sometimes called histiocytosis X. Among these diseases, eosinophillic granuloma of bone usually has a benign course. But, Hand-Schuller-Christian disease and Letterer-Siwe disease are more aggressive form. Especially in Hand-Schuller-Christian disease, both skeletal system and soft tissue may be involved. This is a case with gingivostomatitis and delayed healing of extracted right upper molar area. The microscopic examination from the delayed healing site showed the characteristics of the histiocytosis X consisted of Langerhans cells, eosinophils, and lymphocytes. The continuous examination showed the liver and the lung of the patient had been involved. We experienced a case of Hand-Schuller-christian disease which was one of histiocytosis X treated. with the chemotherapy of vincristine and cyclophosphamide.

Abstract

I. 서론

II. 증례보고

III. 총괄 및 고찰

IV. 요약

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