하악골에 발생한 원발성 상피암 2례

Primary intraosseous carcinoma : report of two cases

The primary intraosseous carcinoma(PIOC) of the jaw is extremely rate condition and I defined as a squamous cell carcinoma arising within the jaw having no initial connection with the oral mucosa and developing from the residues of odontogenic epithelium, according to WHO. We present 2 cases of PIOC in the mandible. The first patient 62-year0old male, visited our hospital with a complaint of a nonhealing extraction wound. A biopsy was performed and the microscopic diagnosis of PIOC was made. the patient underwent combined surgical and radiation therapy with no recurrence for 5 years. The second patients, 21-year-old female, complained a intraosseous lesion in the anterior mandible and a lump of submental area. The intraosseous lesion was resected widely and the result of tissue examination was the calcifying odontogenic cyst. Sine the submental lump remained postoperatively, excisional biopsy of the mass was performed and it has turned out to be metastatic lymph node. So that the first surgical specimen was reviewed and fnal dignosis of PIOC was made. The patient underwent radiotherapy and has remained free of local recurrence for 12 months postopertively. We could obtained the interesting clinical experience, that is, the difficulty of diagnosis and atypical clinical manifestation different with most oral carcinoma.