수종의 소강판이 배양 섬유모세의 세포독성에 미치는 영양에 관한 연구

The effect of the cytotoxicity on cultured fibroblast to various type of miniplate

After the introduction and development of rigid fixation concept on the traumatized, osteomatized facial bone, miniplates have used for last decade. Therfore, commercial miniplates have been made with many shapes and materials. At present, generally using miniplates are stainless steel and titanium miniplate. These materials must have biocompatibility and less cytotoxicity. In this study, to compare to cytotoxicity of these materials, three kinds of titanium miniplates and two kinds of stainless steel miniplates were inserted to he culture media with fibroblast extracted from I.C.R. mouse and were incubated for 2, 4, 7 days. The cytotoxicity was measured by the viable fibroblast cell numbers in the vicinity of the inserted miniplate surface. The results were as follows: 1. Titanium miniplates that consist of high purity of titanium show weak cyctotoxicity. 2. Titanium miniplates that consist of high purity of titanium show weak cytotoxicity. 3. Stainless steel miniplates present relatively weak cytotoxicity.