생선뼈로부터의 BIOCERAMICS(천연 APATITE)에 관한 연구

A study on bioceramics abstracted from fishbone (Natural apatite) : A clinical study on natural apatite graft for adontogenic cyst

Clinical evaluation was performed for 15 cases of odontogenic Cyst patients who were operated from october, 1988 to July, 1990 via natural Hydroxylapatite graft with or without autogenous iliac bone marrow following enucleation of cyst sac and exodontia or apicoectomy of adjacent and causative teeth. 1. Among 15 cases, men were 8(53.3%) and women 7(46.7%), and cysts in upper jaw were 9 cases (60.0%) and 6 cases (40.0%) in lower jaw., 2. In order to enhance the osteogenetic activity, mixture of natural Hydroxylapatite and autogenous iliac bone marrow was grafted for 3 large cystic cavities including 1 case of maxillary cyst and 2 cases of mandibular cysts. 3. Operated wound of 3 cases (20.0%) was infected as postoperative complications, but the prognosis was relatively fair by way of routine dressing technique. Among the infected cases, all of them occured at mandibular lesions and 1 of them was grafted with the mixture of natural Hydroxylapatite and autogenous iliac bone marrow. 4. During postoperative follow-up clinical evidence of resorption of natural Hydroxylapatite was not recognizable, however some cases of dispersed Hydroxylapatite was found in X-ray findings. 5. Infected Hydroxylapatite granules and bone chips were taken out spontaneously by saline irrigation, but the lower margin of graft maintains continuity well throughout the dressing period and denuded wound was fairly healed with ingrowth of soft tissue. 6. Apicoectomized tooth adjacent to denuded wound was sacrificed during healing process, because the distal wall of alveolus of the adjacent tooth was infected and resorbed. 7. The natural Hydroxylapatite(HAP-B) is supposed to be able to be used as a bone substitute without difficulties compared with synthetic Hydroxylapatite in Oral & Maxillofacial surgery with same indication of synthetic Hydroxylapatite.