안면골 골절 환자에 대한 Halothane 마취 후 발생한 Halothane Hepatitis

Halothane hepatitis following halothane anesthesia for facial bone fracture

General anesthesia is necessary to operation in dept. of oral and maxillofacial surgery. Halothane is one of the most commonly used anesthetic agent for general anesthesia. Halothane is a nonexplosive fluorinated hydrocarbon anesthetic agent and structurally similar to chloroform. Halothane has been reported to result in severe hepatic necrosis in a small number of individuals. A genetic predisposition leading to an idiosyncratic metabolic reactivity has been postulated. We experienced and reported 3 cases of halothane hepatitis that occured following halothane anesthesia for facial bone fracture with the review of the relevant literatures.