다형성 선종에 관한 임상병리학적 연구

A clinicopathological study on pleomorphic adenoma

Pleomorphic adenoma is usually of long duration, and presents as a single nodule that is not fixed to the overlying skin or mucous membrane. It grows slowly and is usually asymptomatic. As the name indicates, pleomorphic adenoma is a tumor with a various microscopic picture. A wide surgical excision of the tumor is the recommended treatment. Pleomorphic adenomas are the most persistent of all benign salivary gland neoplasms with a high recurrence rate of 5% to 30%. Although this tumor does not metastasize, but on rare occasion it will terminate in a malignant behaviors like an adenocarcinoma. Author reviewed 65 patients of pleomorphic adenoma at Dept. of Oral and Maxillofacial Surgery, SNUDH during the period from Jan. 1978 to Mar. 1988, and the following results were obtained. 1. The incidence of the tumor was highest between the age of 30 and 60, and affected 45 women and 20 men, suggesting the possibility of high incidence in women. 2. The originating sites of tumor in order were hard palate with 21 patients (32.3 %), hard and soft palate with 15 patients (23.1 %), soft palate with 14 patients (22 %), cheek with 8 patients (12.8 %), and 7 patients from other places, (palate: cheek=50:8) 3. Although the size of the tumor was variable, the incidence was highest between 1㎝ and 3㎝ (60.7 %). 4. 6 cases (9.3 %) were CPAs (carcinoma ex pleomorphic adenoma) among 65 cases. 5. The duration of the most cases exceeded several months and it seemed most patients would not have consulted the doctor soon after they found it.