저출력 레이저 광선이 백서 설창상 치유에 미치는 영향

The effect of low power density laser(as ga)on the wound healing of rat tongue

The purpose of this study was to observe the histopathologic effect on tissue tongue damages following soft laser irradiation. For this study, 42 rats, weighting 180-200gm, were divided into two groups, as experimental group 21 and control group 21. Under general anesthesia with inhalation of ethyl ether, the tongue wounds, approximately 1.5㎜ in depth abd 7㎜ in length, were created on the lateral border of the tongue on right side and crater-like tongue wound which was approximately 7㎜ in length by straight electrosurgical tip was made on left side. Wounds of experimental group were irradiated with As Ga laser (STOMALASER, Sedatelec Co., France) every other day by fourteen day. The animals were sacrificed at every 1, 2, 3, 5, 7, 10, 14, days after wounding and the specimen were sectioned, stained and observed with light microscope. The obtained results from this study were as follows. 1. Overall healing pattern of the wound of the experimental group irradiated with laser was better than that of the control group. 2. Epithelial recovery of wound by surgical blade was shown primary healing procedure at the first day in experimental group and at the third day in control group and the secondary healing was shown similarly in experimental and control group. But the healing pattern was better in experimental group. 3. Recovery of the muscle fibers at the wounds were rapid in the experimental group than the control group and was occured similar to the normal pattern in the tenth day.