KIEL BONE이 家兎의 下顎骨 損傷部 治癒에 미치는 影響

THE EFFECT OF KIEL BONE ON THE HEALING PROCESS OF BONY DEFECT IN RABBITS

The purpose of this experimental study was to observe the rate of new bone formation, tissue tolerance and influence in the healing process of bony defect after Kiel Bone graft in the mandible of rabbits. Sixteen hybrid white rabbits were divided into two groups: Control group and experimental group with Kiel Bone graft (10㎜ in measured diameter). Each of the experimental and control animals was sacrificed on the 1st, 2nd, 4th, 8th weeks postoperation and mandible was removed. Then the specimens were fixed in the 10% neutral formalin solution for 24 hours and decalcified with nitric acid mixed with formalin (1:9). And then embedded in paraffin, sectioned 6㎛ thickness and stained H-E stain. The results were as follows: Minimal new bone formation developed by 1 week after Kiel Bone graft. In control group, new bone formation starts at the 2nd week. At the 4th week, partial resorption of Kiel Bone was noted. The rate and amount of new bone formation were more rapid and abundant in the Kiel Bone graft than control group throughout the eight weeks. There was no foreign body reaction (encapsulation or sloughing) to the grafted Kiel Bone.