Plaster of Paris가 백서하악골 결손부위의 골회복에 미치는 영향에 관한 조직학적 연구

The histological study on the effect of the plaster of paris on the regeneration of mandibular defects of rats

This study was undertaken to evaluate the effect of the plaster of Paris treated on the regeneration of the mandibular bony defect. 30 rats, sprague dawley strain, weighing about 200 gm, were used, devided into control group (15 rats) and experimental group (15 rats). The mandibular bone was penetrated with dental-grade No. 557 bur about 2㎜ in diameter buccolingually. In control group the blood was filled in the surgical defect. In experimental group a pellet of plaster of Paris was implanted in the surgical defect. All rats were sacrificed at 3, 7, 14, 21, and 28 days after surgery, and were examined histologically with light microscope. The obtained results from this study were as follows: 1. In all of the control group and experimental group, marked acute and chronic inflammatory cells infiltration was found at the third day. 2. In control group fibrosis was found at the first week and in experimental group fihrosis and foreign body reaction was found at the only first week. 3. In all of the control group and experimental group, new bone formation was found at the second week and replaced completely with new bone at the fourth week.