Nylon, Silk, Chromic catgut 봉합재료에 대한 백서협점막 조직반응에 관한 실험적 연구

EXPERIMENTAL STUDY ON TISSUE RESPONSE OF BUCCAL MUCOSA TO NYLON, SILK, AND CHROMIC CATGUT SUTURE MATERIALS

This experiment was undertaken to study the tissue response of buccal mucosa to three most commonly used suture materials, nylo, silk, and chromic catgut, using 24 albino rats of a sprague dawley strain, weighing around 180 grams. The three materials - nylon, silk, and chromic catgut in order-were placed in buccal mucosa using 3/8-circle, atraumatic, round needle, paralleling at regular distance. To embed the sutures in the tissues completly, they were cut shorter than the length of mucosa that the needle passed through. The experimental animals were sacrificed every 1,4,7,10,14.21 days postoperatively 4 animals at one time. The buccal mucosa was excised, and the sutures were removed. Specimens were fixed in 10% formalin solution and embedded in paraffin. Serial sections were cut at a thickness of 5 micron, mounted on glass slides and stained using Hematoxylin-Eosin stain. In light microscopic examinations, following results were obtained: 1. Monofilament suture materials showed milder reactions than multifilament sutures, and among multifilament sutures, silk caused core severe reactions than chromic catgut. 2. The healing process began to show from the 4th day in nylon, 10th day in silk, 7th day in chromic catgut, postoperatively. 3. Completely healed tissues were observed on the 7th day in nylon, 21st day in silk. 14th day in chromic catgut, postoperatively. 4. It is considered owing to the absorbability that the chromic catgut caused more severe tissue reactions on the 10th day than on the 7th day, postoperatively.