顔面部에 發生한 Angiolymphoid hyperplasa with eosinophilia(Kimura s disease)의 治驗例

AMGIOLYMPHOID HYPERPLASIA WITH EOSINOPHILIA (KIMURA S DISEASE) ON LEFT FACE

Angiolymphoid hyperplasia with eosinophilia (Kimura s disease) primarily affects the skin of the head and neck and the oral mucosa. While the clinical picture is nonspecific, the variable microscopic tissue pattern often is diagnostic. The etiology is unknown, and treatment is unpredictable. A case is presented in which Kimura s disease was not suspected clinically prior to biopsy. At its early stage, the main findings consist of active vascular proliferation with plump endothelial cells and varying degrees of lymphocytic, histiocytic, and eosinophilic infiltration. The lesion at its later stage features hyperplastic blood vessels with inconspicuous endothelial cells, well-formed lymphoid follicles, and varying degrees of lymphocytic and eosinophilic infiltration. Blood eosinophilia is frequently seen.