한국인의 舌腫瘍에 관한 임상 및 병리조직학적 연구

CLINICAL AND HISTOPATHOLOGICAL STUDIES ON THE TONGUE TUMORS IN KOREANS

The author has studied clinically and histopathologically on the 132 cases of tongue tumors in Koreans during the period of Jan., 1964 to Dec., 1976. Those materials were obtained from the Department of Pathology, College of Medicine of Yonsei University. The results of these studies are as follows; 1. Among the 132 cases of tongue tumor, benign tumors were 62 cases(47%) and malignant tumors were 70 cases(53%). 2. In the 62 cases of benign tumor of the tongue, the highest incidence was 22 cases(35.5%) of papilloma, and the lowest was one(1.6%) of Myxochondroma. 3. In the 70 cases of malignant tumor of the tongue, carcinomas were 67 cases(95.7%) and sarcomas were 3 cases(4.3%). Of these, the highest incidence was 59 cases(84.4%) of epidermoid carcinoma, and the lowest was each one(1.4%) of anaplastic carcinoma, angiosarcoma, reticulum cell sarcoma and malignant hemangioendothelioma. In 59 cases of epidermoid carcinoma well-differentiated group was 35 cases(59.3%), moderately well-differentiated group was 13 cases(22.0%) and poorly-differentiated group was 11 cases(18.7%). 4. The sexual incidence was relatively same in benign tumor, but male was predominant in malignant tumor(2.5:1). As to the age distribution of tongue tumor, each decade group showed relatively same distribution in benign tumor, but 40-60 decade group showed the highest incidence(56 cases or 80%) in malignant tumor. Average age for tongue tumor was 37.8 years in benign tumor and 53.6 years in malignant tumor. 5. The most common complaint of benign tumor was visible mass(45 cases or 72.6%), followed by pain and discomfort(9 cases or 14.6%) and foreign body sensation(3 cases or 4.8%), etc.. Malignant tumor showed 29 cases(41.4%) of visible mass, 21 cases (30.0%) of ulceration and 11 cases(15.7%) of pain & discomfort, etc.. 6. The most common site of origin of benign tumor was anterior 23 portion(29 cases or 46.9%), followed by dorsum(19 cases or 30.6%) and posterior 1/3 portion(8 cases or 12.9%) etc.. Malignant tumor showed 41 cases(58.6%) of anterior 2/3 portion, 16 cases(22.9%) of posterior 1/3 portion and 4 cases(5.7%) of dorsum, etc.. 7. The size of lesion was 2cm. or less in most cases(66.1% in benign tumor and 54.3% in malignant tumor). 8. Among the 36 cases of malignant tumor which were able to determine TNM classification, the highest incidence was 12 cases(33.3%) of stage Ⅲ, and the lowest was 3 cases(8.3%) of stage Ⅱ. The more posterior lesion was and the more large lesion was, the more its metastatic rate was increased.