두경부 암환자의 방사선요법시 구강내 캔디다속에 대한 연구

STUDY OF CANDIDA GENUS ON PATIENTS WITH HEAD AND NECK CANCER DURING RADIOTHERAPY

80 cases of head and neck cancer were subjected to oral culture for Candida species during radiotherapy in Yonsei Cancer Institute and Korea atomic Hospital. And 40 cases of healthy People were cultured as a control group. Irradiation was carried out using Co 60 TeleTherapy Units in all patients. Classification of Candida Genus was done using API 20 Candide Kits. The results were as follows, 1. Control group was revealed with 22.5 % positive culture of Candida. 2. Positive culture of Candida species on patients irradiated under 3000R was 30.8%. 3. Positive culture of Candida species on patients irradiated over 3000R was 50.0%. 4. 35 Candida species of eighty irradiated patients were consisted of 28 of C.albicans, 4 of C. tropicalis, each 1 of C.krusei, C. zeylanoids, and undetermined Candide sp. 5. Nine Candida species of forty control group were consisted of 5 of Candida albicans, 2 of C. guilliermondii, each 1 of C. zeylanoids and C. parapsilisis.