This study aimed to find out the effect of freeze -drying leek against cadmiurn poisoning on the cholesterol and enzyme activities in serum and superoxide radical, SOD and catalase in liver and kidney of the rnale rats during the administrered period. ln this experiment, male rats of SPragμe-Dawley strain were used. The rats were divided into 3 groups which were fed different1y either for 5 weeks or for 10 weeks : basal diet, basal diet and cadmium in water and 3 % leek added diet and cadmium in water. Cadmium was administered ad libltum 100 ppm CdCh in water. The followings are the results of this experiment. l. Leek reduced the cholesterol and the activities of GPT increase resulted from cadmium treatment. 2. Leek reduced the rate of cadmium in liver and kidney. 3. Leek reduced the activities of SOR and catalase in liver and kidney, while it enhanced the activities of SOD. 4. Leek reduced the necrosis and swelling in liver and kidney casused by cadmium treatment. This experiment showed that leek -addition group had protective effect agair:st cadmium pois oning and increased ALPase activities in serum. Leek alleviated GPT activities m serum and cad•rnium concentration, necrosis, and swelling in liver and kidney, Therefore, this experiment con c1uded that leek has defenslve power against cadmium poisoning.
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II. 재료 및 방법
lll. 실험 결과 및 고찰
lV. 결 론
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