초임계 이산화탄소 용매하의 요소부가법에 의한 어유지방산으로부터 EPA와 DHA의 분리

Separation of EPA and DHA from Fatty Acid of Fish Oil by Urea Adduct Formation Using Supercritical Carbon Dioxide Solvent

Separation of EPA and DHA from fish oil fatty acid ethyl ester (FAFE) by urea adductive crystallization method was carried out in the supercritical carbon dioxide (SC $CO_2$ 수식 이미지) as a solvent. Our results showed that SC $CO_2$ 수식 이미지 is a good candidate as a solvent in the urea adductive crystallization to separate FAFE by the number of unsaturated bonds. Compared to the separation process using methanol. SC $CO_2$ 수식 이미지 yielded better performance in the overall selectivity of EPA and DHA. The effect of process variables on separation of EPA and DHA was discussed in detailed. A hybrid technology of SC $CO_2$ 수식 이미지 fractionation and urea adductive crystallization with SC $CO_2$ 수식 이미지 was conformed as a viable process to separate and concentrate EPA and DHA from fish oil.