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인돌 유도체 II. Indolylacrylophenone 유도체의 가수분해 반응에 대한 메카니즘과 그 반응 속도론적 연구

Indole Derivatives II. The Kinetics and Mechanism of the Hydrolysis of Indolylacrylophenone Derivatives

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The kinetics of the hydrolysis of indolylacrylophenone derivatives(IA) was investigated by ultraviolet spectrophotometry in 30% dioxane-H₂O at 25℃. Rate equations were obtained over a wide pH range. On the basis of rate equation, general base catalysis and Hammett s plot, the mechanism of hydrolysis to the (IA) were proposed : Below pH 3.0, the hydrolysis of (IA) was proportional to hydronium ion concentration, between pH 4.0~9.0 neutral water molecule and hydroxide ion were added to carbon-carbon double bond and over pH 10.0 hydrolysis of (IA) was proportional to hydroxide ion concentration.

ABSTRACT

I. 서론

II. 실험

III. 결과 및 고찰

IV. 결론

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