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High Performance Liquid Chromatography를 이용한 CefatrizineㆍPropylene Glycol 의 분리 및 정량

Separation and Determination of CefatrizineㆍPropylene Glycol by High-performance Liquid Chromatography

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The fast separation and determination of cefatrizineㆍpropylene glycol and inmpurities - TACA: 7-amino-3-(1,2,3-triazol-4-yl)thiomethyl-3-cephem-4-carboxylic acid and 7-ACA; 7-amino cephalosporanic acid - was performed by the high poerformance liquid chromatography using octadecyl siland (ODS) column. Methanol and ammonium phosphate buffer [0.03M(NH₄)₂ HPO₄, (pH 7.5)] was used analyze, as eluent. The experimental value of the contents of cefatrizineㆍpropylene glycol and impurities agree with the theoretical value of those.

ABSTRACT

I. 서론

II. 재료 및 방법

III. 결과 및 고찰

IV. 결론

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