界面活性 아미노싸이클리톨 誘導體의 合成

Synthesis of Surface Active Aminocyclitol Derivatives

Inosamine(deoxyaminoinositol) stereomers such as scyllo-inosamine, myo-inosamine-2,epi-inosamine-2 and myo-inesamine-4 have been synthesized from myo-inositol (1,2,3,5/4,6-hexahydroxycyclohexane) And sixteen of quaternary ammonium salt type deoxyaminoinositols such as dimethylalkyl-deoxy-scyllo-inosityl-, dimethylalkyl-2-deoxy-2-myo-inosityl-, dimethylalkl-2-deoxy-2-epi-inosityl and dimethylalkyl-4-deoxy-4-myo-imosityl ammonium chlorides with straight chain alkyl group having from eight to fourteen carton atoms have been synthesized from four kinds of the imosamine stereomers. The isolation and detection of dimethylalkyl-deoxy-inosityl ammonium chlorides have been investigated by column chromatography, paper chromatography, infrared absorption spectra and elementary analysis, respectively.