石茸버섯(Gyrophora Esculanta)에 含有되어 있는 肝臟 및 血漿 cholesterol低下物質에 關한 硏究 (第2報)

Studies on the Substances Contained in Gyrophora Esculenta Lowering Plasma and Liver Cholesterol Levels (Part II)

백쥐의 飼料에 석이버섯의 水溶性 및 EtOH 抽出物을 添加하여 脂質代謝 및 cholesterol代謝에 미치는 영향을 檢討한 結果, 다음과 같은 結論을 얻었다. ① 肝臟 및 血漿 cholesterol 低下作用에 관해서는 水溶性 抽出物이나 EtOH 抽出物이 同時에 有效하다는 結果를 얻었다. 그리고 EtOH 抽出物이 水溶性 抽出物보다 약간 높은 경향을 보였다. ② 이 cholesterol 低下作用에 관여하는 有效性物은 물이나 EtOH의 抽出에 따라서 어느 쪽의 추출액으로도 移行되는 性質을 가지고 있다고 推定된다.

As the previous report, by the administration of Sogi, Gyrophoraesculenta, to rats, cholesterol levels in liver and plasma were lowered. To know the Characteristics of the effective material contained in Iwatake, the aqueous and the alcoholic extracts were prepared, and these extracts were miked in the diet. After the feeding for 6weeks, cholesterols in liver and in plasma were determined. Either the aqueous or the alcoholic extracts administered groups showed a little low value as to these cholesterol levels compared with the value of group without the extract, but these values of alcoholic extract administered group were lower than those of aqueous extract group. From this result, it was assumed that this effective material would be the organic compound with hydrophilic groups.