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신경변성질환과 ABO혈액형의 연관성

The Association of Neurodegenerative Diseases and ABO Blood Group

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The antigens of the ABO blood group system (A, B and H determinants) are expressed on red blood cells and on a variety of other cells and tissues including neurons. Recently, evidence is accumulating that ABO antigens may interplay with the pathogenesis of human diseases, including infections, cancers, and cardiovascular diseases. In this review, the possible role of ABO system is elucidated particularly in the ageing-related neurodegenerative disorders including Parkinson’s disease, Alzheimer’s disease, cognitive impairment and longevity.

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