연안해수에서 분리된 항균제 내성세균의 특성

Charaterization of drug resistance bacteria isolated from the southern coastal sea water of Korea

The distributions of drug resistance bacteria were investigated in 28 sites of the southern coastal sea water of korea. Drug resistance bacteria were isolated using the sea water nutrient agar media containing the 10㎍/㎖ of ampicillin(AM), 25 ㎍/㎖ of streptomycin(SM), and 250㎍/㎖ of sulfonamide(SA). Over 30% of total bacteria showed AM and SM resistance in 8 and 7 sampling sites, respectively but SA resistance only in 2 sites. Two hundreds and ninty isolates were divided to 6 types of resistance pattern from 1 to 6 kind of drugs. Over 60% of the resistance bacteria showed multiple resistant to more than 3 drugs. About 70% of multiple drug resistance bacteria had the transferable resistance marker and the markers were AM, kanamycin, oxytetracyclin resistance. The resistance bacteria to oxytetracycline or oxolinic acid appeared around fish farms developed well.