알코올 의존 환자에서 시점간 선택에 관한 연구

Intertemporal Choice in Alcohol Dependence

Objectives ： The objectives of this study were to investigate intertemporal choice in patients with alcohol dependence and to examine whether impulsivity or working memory is related to intertemporal choice in patients with alcohol dependence. Methods ： Fifty alcohol dependence patients and fifity healthy controls were recruited in this study. All participants were male. All patients were subjected to the following tests : Delay Discount-ing Task (DDT), the Wisconsin Card Sorting Test (WCST), the Barratt Impulsiveness Scale-11 (BIS-11), and the Korean version of Michigan Alcohol Screening Test (MAST-K). Results ： Com-pared to the control group, the alcohol dependence group showed higher delayed reward discounting rate in DDT. The performance on the WCST of alcohol dependence group was significantly poorer than that of the control group. Alcohol dependence group scored higher than controls in the total score of the BIS-11 and the motor subscale scores. The perseverative error in WCST was significantly correlated with the 1 day indifference point (r=-0.505, p＜0.01) and 2 day indifference point(r=-0.388,p＜0.01) in DDT. However, the indifference point in DDT did not show significant relationships with the score of BIS-11 or MAST-K within the alcohol dependence group. Conclusion : Intertemporal choice in patients with alcohol dependence had more delayed reward discounting compared to the control group. Delayed discounting and impaired working memory were significantly correlated. Delayed discounting and self-report mea-sure of impulsivity or alcohol dependence were not correlated.