정신분열병 환자에서 흡연과 삶의 질의 연관성

Relationship between Smoking and Quality of Life in Patients with Schizophrenia

Objectives：We investigated the relationship between smoking and quality of life in patients with schizophrenia. Methods： One hundred stable outpatients with schizophrenia according to the DSM-IV-TR criteria were included. The KmSWN was used for evaluating the subjective quality of life while the K-QOLS was used to assess the objective quality of life. The psychopathology of each patient was assessed by the PANSS. The K-PSP was used for evaluating social function. The severity of ni-cotine dependence in smokers was evaluated with the K-FTND. For statistical analysis, t-test, multivariate analysis (MANCOVA), correlation analysis were conducted. Results：Quality of life of the smokers had significant lower scores in physical and mental functioning factor in KmSWN and had tendency of lower total score in total KmSWN. The total score and three subscale score in K-QOLS were lower in smokers than nonsmokers but there were no differences after MANCOVA. There was significantly correlated between K-FTND and dissatisfaction factor in Km-SWN. K-PSP and K-QOLS were positively correlated. Conclusion：These results suggested that smokers with schizophrenia have lower quality of life both subjectively and objectively. The increased smoking severity is associated with the poor subjective quality of life. These results suggest that attention and intervention for smoking is an important part of treatment for patients with schizophrenia in order to improve their quality of life.