알코올 의존 환자의 혈중 탄수화물결핍 트랜스페린 변화에 대한 4주간 추적 연구

Follow-up Study for the Change of Serum Carbohydrate-Deficient Transferrin Levels in Patients with Alcohol Dependence

This purpose of this study is to explore the factors influencing the change of plasma CDT after a 4-week abstinence in patients with alcohol dependence. The subjects were 79 alcohol-dependent inpatients whose % CDT was greater than 2.6% at the baseline. In the monitoring of % CDT at the 4-week follow-up, 35 patients (32 male and 3 female) showed lower than the cutoff value of 2.6%, and 44 patients (37 male and 7 female) showed still less than that. The change of %CDT was associated with the age that the patients started drinking, certain he-patic indexes such as AST, ALT, and GGT in the baseline, and alcoholic cirrhosis. Otherwise, baseline %CDT, mean amounts and duration of drinking, BMI, amount of daily smoking, alcoholic hepatitis, and fatty liver were not associated with the change of %CDT. Further extensive studies are needed.