폐경기 여성에서 DXA를 이용한 Lateral Vertebral Assessment의 유용성

The Usefulness of Lateral Vertebral Assessment with DXA in Postmenopausal Women

Purpose : Osteoporosis is defined as a skeletal disorder characterized by decreased bone strength and increased risk of fracture. Although many vertebral fracture are clinically silent. they are associated with increased risk for subsequent osteoporotic fracture in postmenopausal women. We evaluated the ability of clinicians using dual-energy Lateral vertebral assessment(LVA) to detect prevalent vertebral fracture. Materials and methods : Dual-energy LVA and conventional thoracic and lumbar spine radiography were concurrently obtained in 158 postmenopausal women. Using an established visual semiquantitative system. vertebral fracture were identified individually by a radiologist clinicians on LVA image, and the results were compared with spinal radiograph evaluation by two expert radiologist. and we retroprospectively compare each BMD category. Results : LVA clinicians correctly identified 94% (76/72) of radiographically defined grade 1~3 vertebral fracture among 158 subject. Women(76) with vertebral fracture were divided up by BMD category, osteoporosis in 85%(65), osteopenia in 15%(11). Specifically most of women with vertebral fracture don’t have back pain. they were only 38%(29/76) Conclusion : Thoracic and lumber spine x-ray are the gold standard for vertebral fracture. LVA provides a more practical screening tool due to the lower radiation(0.083mSv) dose and its availability at the point of service for women attending for DXA. May be screening tool for osteoporosis clinical trial in postmenopausal women.