Pre-eclampsia is known to cause considerable maternal morbidity and mortality. Thus, many studies have examined the etiopathogenesis of pre-eclampsia. While many pathophysiological factors related to pre-eclampsia have been identified, the precise etiopathogenesis of pre-eclampsia remains unclear. Numerous studies have identified factors for the early prediction for pre-eclampsia to lead to preparation and closer observation on pre-eclampsia when it occurs. This article reviews on current studies of biomarkers and genetic factors related to pre-eclampsia, which may be important for developing strategies for early prediction of pre-eclampsia.
Abstract
Introduction
Angiogenic Factors
Pregnancy-associated Plasma Protein-A
Inhibin-A and Activin-A
Placental Protein 13
Cystatin C
Pentraxin
P-Selectin
Genetic Markers for Pre-eclampsia
Cell-free DNA
Conclusion
References
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