조영제 부작용 분석

Analysis of Adverse Reactions to Contrast Media

Purpose To evaluate the prevalance rate and symptoms of risk factors of the adverse reactions m patients after contrast injection during CT examinations. Materials and Methodes Between january 2005 and december 2005, 103, 343 patients who received intravenous contrast administration during CT scans at Asan Medical Center. We evaluated the prevalance rate, symptoms of risk factors of the adverse reactions in patients based on reviewing medical records. Results The results of this study are as follows; 1. Adverse reactions occurred in 447 of 103,343 patients(0.43%). 2. Incidencs of severe adverse reactions occurred in 171 of 103,343 patients(0.17%) and very severe adverse reactions occurred in 1 of 103,343 patients(0.0001%). 3. Clinical signs of adverse reactions were most commonly dermatologic problems(40.4%) such as urticaria and itching, followed by systemic problems(30.5%), nervous problems(9.6%), respiratory problems(9.5%), and so on. Conclusions Serious adverse reaction to CM are fortunately fatal reactions are extremely rare with incidence of 1 in 170,000 contrast examinations. History of previous serious reaction to contrast media, bronchial asthma or multiple allergies are important risk factors for developing major reactions to contrast administration. A voiding contrast media administration in patients at high risk of serious reaction is advisable but if the administration is deemed essential all precautions should be implemented and measures to treat serious reactions should be rapidly available.