Coenzyme Q₁₀의 신체내에서의 생리학적 작용

A Review of Functional Activities of Coenzyme Q₁₀

Coenzyme Q₁₀ is an essential part of the cellular machinery like mitochondria used to produce ATP which provides the energy for living organism. It is a functional element in all cell membranes. Coenzyme Q₁₀ functions in its reduced form as an antioxidant. improving exercise performance. protecting biological membranes and serum LDL from lipid peroxidation. Coenzyme Q₁₀ directly reacts with free radicals and regenerates the activity of vitamin E by reducing the alpha-tocopheryl radical. Coenzyme Q₁₀ is highly concentrated in heart muscle. liver and kidney. Statin-induced coenzyme Q₁₀ deficiency is preventable with supplemental coenzyme Q₁₀. The congestive heart failure has been strongly correlated with significantly low blood and tissue levels of coenzyme Q₁₀. Coenzyme Q₁₀ significantly improved heart muscle function while producing no adverse effects or drug interactions. Coenzyme Q₁₀ was effective in lowering systolic and diastolic blood pressure. High doses intake of Coenzyme Q₁₀0 appeared to slow the progressive deterioration of function in early Parkinson’s disease. Coenzyme Q₁₀ supplementation increased total coenzyme Q₁₀ concentration in the slow-twitch muscles, and was useful for reducing exhaustive exercise-induced muscular injury by enhancing stabilization of muscle cell membrane. But, in highly trained athletes(triathletes. marathon and bicycle racers). Coenzyme Q₁₀ supplements had no measurable effect on oxygen uptake or exercise-induced fatigue. The plasma levels of coenzyme Q₁₀ were affected by regular exercise, so more research about the relationship between human health and Coenzyme Q₁₀ is needed.