신체 구성비와 인지기능과의 연관성 :

Relationship between Body Composition and Cognitive Function : Using Bioelectrical Impedance Analysis

Objective：Body composition is measured using bioelectrical impedance analysis (BIA), and correlation between the result of BIA and cognitive function is analyzed. Methods：A total of 118 elderly (46 male, 72 female) were recruited. They were divided into three groups; normal (n=33), mild cognitive impairment (n=42), and Alzheimer’s dementia (n=43) according to the diagnostic criteria. Skeletal muscle mass, body fat mass, and fat-free mass were measured using a BIA device, and were converted to the ratio of body weight. All participants underwent Korean version of Mini-Mental State Examination (MMSE-K). Results：In pearson correlation analysis, skeletal muscle percentage (SMP) and fat-free mass percentage (FFMP) were positively correlated with MMSE-K score (r=0.309, p=0.001; r=0.245, p=0.008), and body fat percentage was negatively correlated (r=-0.258, p=0.005). In multiple regression analysis, SMP (β=2.012, t=4.457, p＜0.001) and FFMP (β=-1.733, t=-3.838, p＜0.001) were selected as the best predictors of changes in MMSE-K score (R2=0.198). Conclusion：Reduced skeletal muscle and increased body fat correlate with decreased cognitive function, suggesting the need for prevention of frailty and early diagnosis of cognitive impairment.