차수수 껍질 주정 추출물의 항산화 활성과 식후 혈당 상승 억제 효과

Antioxidant and Anti-Hyperglycemic Effects of Ethyl Alcohol Extracts from Hull of Sorghum Bicolor (L.) Moench

Inhibition of small intestinal α-glucosidases involved in the digestion and absorption of carbohydrates can significantly decrease the postprandial increase of blood glucose level after a mixed carbohydrate diet. In the current study, we evaluated the inhibitory activities of extracts from Sorghum bicolor (L.) Moench Hull (SMH) against rat small intestinal α-glucosidases. Furthermore, to determine the oxygen radical absorbance capacity (ORAC) in the Sorghum bicolor (L.) Moench Hull (SMH), phenolic content and ORAC value were measured by spectrophotomer and fluorescence detector. Consequently, ethanol extract from hull tested had a high α-glucosidase inhibitory activity. These in vitro studies indicate that hull extracts from Sorghum bicolor (L.) Moench which has antioxidant and α-glucosidase inhibitory activity have the potential in the development of effective anti-diabetic agents.