혈액검체에서 분리된 Streptococcus oralis 의 항균제 내성

Antimicrobial Resistance of Streptococcus oralis Isolates from Blood Specimens

A rapid increase in antimicrobial resistant bacteria has become a serious problem in many countries including Korea. Streptococcus oralis is an early colonizer of the oral cavity that contributes to dental plaque formation. Many different genotypes can coexist in the same individual and cause opportunistic infection such as bacterial endocarditis. The aim of this study was to determine the prevalence of antimicrobial resistance among blood culture isolates of S. oralis in Korea. S. oralis had been isolated during the period from January to December in 2013. The resistance rate of 36 clinical isolates of S. oralis were 25.0% to penicillin, 22.2% to ampicillin, 19.4% to cefotaxime, 19.4% to cefepime, 2.8% to meropenem, 5.5% to clindamycin, 27.8% to chloramphenicol, 47.2% erythromycin, and 47.2% to tetracycline. None was resistant to vancomycin. Strict infection control and active surveillance program will be required to manage the antimicrobial resistance problem.