노화와 내분비계

Aging and Endocrine System

The endocrine system is known to be involved to an aging process by gene mutations of endocrine signaling pathways. Complex changes multiple hormones within the endocrine system also occur in aging individuals. Changes in the concentration of hormones cause clinical symptoms and also impact health and disease. Hormone deficiencies with aging, result in vasomotor sypmptoms, fatigue, psychological symptoms, poor libido, decreased bone mass and lean body mass, and increased fat mass and insulin resistance. Many studies have been carried out to evaluate the effects of hormonal supplements on reversing or slowing down the aging process. This review explores the role of the endocrine system during this aging process and the changes of various hormones and resulting clinical significances in aging individuals.