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학술저널

仔豚설사중에서 분리된 大腸菌의 抗元과 免疫原性

Antigenicity and immunogenicity of enterotoxigenic Escherichia coli isolated from diarrheal piglets in Korea - A current research

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Enterotoxigenic Escherichia coli (ETEC) producing heat-labile (LT) and/or heat-stable (ST) enterotoxins causes “acute diarrhoeal diseases” in man and animals. In the control of “acute diarrhoeal diseases” particulary in the young animals, piglet, calf and lamb, an immunopropylaxis is a great value before chemotherapy because both enterotoxins, LT and ST are controlled by transmissible plasmids as well as with multiple drug resistance gene, “R factor”. In this review, a pathogenesis of colibacillosis, antigenicity and immunogenicity of E. coli, antibiotic susceptibility of ETEC strains isolated from diarrhoeal piglets, representative OK serotypes of vaccine strains and their immunoprophylactic efficacy were discussed.

ABSTRACT

서론

I. 대장균감염증(Colibacillosis)의 발병기전

II. ETEC의 항원구조

III. ETEC에 의한 자돈설사증에 대한 면역원

IV. 국내분리 ETEC의 OK혈청형 및 K88 항원

V. OK 다가백신의 면역효과

VI. 세균간섭현상에 의한 설사증예방

결론

參考文獻

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