Cyprinus caprio와 oncorhynchus mykiss의 세균성 질병에 대한 퀴놀론계 항균물질 ciprofloxacin의 항균효능 및 안전성에 관한 연구

A study on efficacy and safety of quinolone antibacterial(ciprofloxacin) to bacterial diseases in cultured fish, cyprinus caprio and oncorhynchus mykiss

A study on quinolone antibacterial (ciprofloxacin) was performed to use for the drug of fisheries. Ciprofloxacin was proved excellent in antibacterial activity and resistance against fish pathogens when compared with the existing antibacterials. And any side effect was not observed during the period of indicated use. An outline of MIC (Minimal Inhibitory Concentration) was ＜0.01~0.02㎛/ml, TLm48h value were more than 5,000 ppm in Mirror carp (Cyprinus caprio) and rainbow trout (Oncorhynchus mykiss). The residual time of fish body was less than 23 days. So we can treat some fish bacterial disease of fish by the dosage of 100g/day/ton of fish body weight for 3 days and ciprofloxacin is thought to be used effectively and widely against most bacterial fish pathogens.