CT검사 시 방사선 흡수선량에 따른 혈액학적 변화 관찰

Radiation absorbed dose during CT examinations in accordance with observed changes in haematological

목적 환자의 CT검사 시 흡수선량에 따른 혈액수치를 검사 전과 검사 후로 나누어 흡수선량범위에 따른 급성장애에 관한 혈액학적 변화 관계를 알아보고자 한다. 대상과 방법 2011년 5월부터 7월까지 CT검사를 시행한 병동환자(남: 74명, 여: 53명-평균연령 60.9세)를 중심으로 검사 전 혈액검사 검사 후 1~2일 후 혈액검사결과를 수집하여 흡수선량 범위(500mGy 이하, 500~1000mGy, 1000 mGy 이상)를 구분, 환자의 급성장애에 관한 혈액수치를 비교 분석하였다. *사용장비: GE Light VCT (Dose Report: DLP <mGy-cm>) 결과 1. CT 검사 전과 검사 후(혈액검사 1~2일 후 이내) 혈액수치결과. 127명(남: 74명, 여: 53명) 평균나이: 60.9세 평균Dose: 846mGy-cm WBC(5.6→4.9) 10³/mm³ 12,5% 감소, RBC(4.8→4.5) 106/mm³ 6,3% 감소, Platelet(l76.9→165.6) 10³/mm³ 6.4% 감소, Lymphocyte(20.7%→19.2%) 7.2% 감소. 1) 500mGy-cm 이하:(남: 23명, 여: 13명) 평균나이: 60.2세, 평균Dose DLP 452 mGy-cm WBC(5.4→5.1) 10³/mm³ 5.6% 감소, RBC(5.1→4.9) 10&#8310;/mm³ 3.9% 감소 Platelet(185.1→178.3) 10³/mm3 3.7% 감소, Lymphocyte(18.2%→17.8%) 2.2% 감소. 2) 500mGy~1000mGy-cm: (남: 27명, 여: 15명) 평균나이: 60.5세 평균 DLP Dose: 867mGy-cm WBC(5.8→5.2) 10³/mm3 10.3% 감소, RBC(4.5→4.2) 10&#8310;/mm³ 6.7% 감소 Platelet(191.4→183.2) 10³/mm3 4.3% 감소, Lymphocyte(20.9%→19.4%) 7.2% 감소. 3) 1000mGy-cm 이상 -(남: 30명, 여: 19명) 평균나이: 61.2세 평균 DLP Dose: 1356 mGy-cm WBC(5.7→4.6)10³/mm³ 19.3% 감소, RBC(4.7→4.3) 10&#8310;/mm³ 8.5% 감소, Platelet(154.2→135.4) 10³/mm³ 12.2% 감소, Lymphocyte(23.1%→20.3%) 12.1% 감소. 결론 CT검사 전과 검사 후 흡수선량의 범위에 따른 혈액수치를 비교해 본 결과 검사 전에 비해 WBC, RBC, Platelet Count, Lymphocyte 수치 모두 검사 후에 혈액수치가 감소하였으며 흡수선량이 높은 구간에서 혈액수치의 감소폭이 비교적 높게 나타나는 걸 확인할 수 있었다.

I. Purpose Absorbed dose during CT examinations of patients according to blood tests before and after the test is divided into levels. According to the absorbed dose range for acute disorders To evaluate the relationship between changes in hematology. II. MATERIALS and METHODS May to July 2011 who underwent CT scans ward patients (M: 94, F: 63 people - average age 60.9 years) before checking into the center of one to two days after a blood test after the test results of blood tests were collected. Absorbed dose range(less than 500mGy, 500~1000mGy, more than 1000mGy) separate the patients with acute disorders of On the blood levels were compared. *Equipment used: GE Light speed VCT (Dose Report: DLP <mGy-cm>) III. Result 1. CT scans before and after the test (blood test within 1-2 days)127 People (M: 74, F: 53), Average age: 60.9, Average DLP Dose: 846 mGy-cm WBC(5.6→4.9) 10³/mm³: 12.5% reduction, RBC(4.8→4.5) 106/mm³: : 6.3% reduction, Platelet(176.9→165.6) 10³/mm³: 6.4% reduction, Lymphocyte(20.7%→19.2%): 7.2% reduction. 1) Less than 500 mGy-cm People(M:23, F:13) Average age: 60.2, Average DLP Dose: 452 mGy-cm WBC (5.4→5.1) 10³/mm³: 5.6% reduction, RBC(5.1→4.9) 106/mm³: 3.% reduction Platelet(185.1→178.3) 10³/mm³: 3.7% reduction, Lymphocyte (18.2%→17.8%): 2.2% reduction 2) 500 mGy~1000 mGy-cm People(M:27, F:15), Average age:60.5, Average DLP Dose: 867 mGy-cm WBC(5.8→5.2) 10³/mm³: 10.3% reduction, RBC(4.5→4.2)106/mm³: 6.7% reduction Platelet(191.4→183.2) 10³/mm³: 4.3% reduction, Lymphocyte(20.9%→19.4%): 7.2% reduction 3) More than 1000mGy-cm People(M:30,F:19) Average age: 61.2, Average DLP Dose: 1356 mGy-cm WBC(5.7→4.6) 10³/mm³: 19.3% reduction, RBC(4.7→4.3) 106/mm³: 8.5% reduction, Platelet(154.2→135.4) 10³/mm³: 12.2% reduction, Lymphocyte (23.1%→20.3%): 12.1% reduction. IV. Conclusion CT scans before and after the test to the range of absorbed dose results in blood levels were compared. Before the test, compared to the WBC, RBC, Platelet Count, Lymphocyte numbers in blood levels after checking all the Decreased. In particular, the higher the absorbed dose to blood levels were more significantly reduced actin know.