
Evaluation of the hybrid-dynamic conformal arc therapy technique for radiotherapy of lung cancer
- Sung Joon Kim Jeong Won Lee Min Kyu Kang Jae-Chul Kim Jeong Eun Lee Shin-Hyung Park Mi Young Kim Seoung-Jun Lee Soo-Ho Moon Byoung-Soo Ko
- 대한방사선종양학회
- 대한방사선종양학회지
- 제36권 제3호
- 등재여부 : KCI등재
- 2018.07
- 241 - 247 (7 pages)
Purpose: A hybrid-dynamic conformal arc therapy (HDCAT) technique consisting of a single half-rotated dynamic conformal arc beam and static field-in-field beams in two directions was designed and evaluated in terms of dosimetric benefits for radiotherapy of lung cancer. Materials and Methods: This planning study was performed in 20 lung cancer cases treated with the VERO system (BrainLAB AG, Feldkirchen, Germany). Dosimetric parameters of HDCAT plans were compared with those of three-dimensional conformal radiotherapy (3D-CRT) plans in terms of target volume coverage, dose conformity, and sparing of organs at risk. Results: HDCAT showed better dose conformity compared with 3D-CRT (conformity index: 0.74 ± 0.06 vs. 0.62 ± 0.06, p < 0.001). HDCAT significantly reduced the lung volume receiving more than 20 Gy (V 20 : 21.4% ± 8.2% vs. 24.5% ± 8.8%, p < 0.001; V 30 : 14.2% ± 6.1% vs. 15.1% ± 6.4%, p = 0.02; V 40 : 8.8% ± 3.9% vs. 10.3% ± 4.5%, p < 0.001; and V 50 : 5.7% ± 2.7% vs. 7.1% ± 3.2%, p < 0.001), V 40 and V 50 of the heart (V 40 : 5.2 ± 3.9 Gy vs. 7.6 ± 5.5 Gy, p < 0.001; V 50 : 1.8 ± 1.6 Gy vs. 3.1 ± 2.8 Gy, p = 0.001), and the maximum spinal cord dose (34.8 ± 9.4 Gy vs. 42.5 ± 7.8 Gy, p < 0.001) compared with 3D-CRT. Conclusions: HDCAT could achieve highly conformal target coverage and reduce the doses to critical organs such as the lung, heart, and spinal cord compared to 3D-CRT for the treatment of lung cancer patients.
Introduction
Materials and Methods
Results